Methanolic extract of Moringa oleifera leaf and low doses of gamma radiation alleviated amiodarone-induced lung toxicity in albino rats

H Hasan, NM Thabet… - Archives of Biological …, 2016 - serbiosoc.org.rs
… the exchange of oxygen and carbon dioxide between the atmosphere and … vitro study of
lovastatin interactions with amiodarone and with carbon tetrachloride in isolated rat hepatocytes

[HTML][HTML] High-content analysis of in vitro hepatocyte injury induced by various hepatotoxicants

NTT Tham, SR Hwang, JH Bang, H Yi… - Journal of Veterinary …, 2019 - ncbi.nlm.nih.gov
… responses between the two types of hepatocytes. O'Brien [15] … In this study, mitochondrial
impairment was determined by … In this study, both hepatocyte types exhibited mild or severe …

[PDF][PDF] Quercetin and a review on its importance

VV Nimbalkar, JM Hemnani… - Oxidative …, 2019 - wjpr.s3.ap-south-1.amazonaws.com
… are chances of drug-drug interactions or it may also interfere … of hepatotoxic insults, including
carbon tetrachloride (CCl4), … Oxidative damage induced by ethanol in rat hepatocytes has …

[HTML][HTML] Drug-induced liver toxicity and prevention by herbal antioxidants: an overview

D Singh, WC Cho, G Upadhyay - Frontiers in physiology, 2016 - frontiersin.org
… Drug composition and drug-drug interaction may also be a reason for increased risk of drug-…
CYP-mediated reduction of halogenated hydrocarbons, for example, carbon tetrachloride or …

[HTML][HTML] 3D in vitro human organ mimicry devices for drug discovery, development, and assessment

A Rodriguez-Garcia, J Oliva-Ramirez… - Advances in Polymer …, 2020 - hindawi.com
… CYP3A1 and CYP2C11 Rat hepatocyte primary cell culture … When acetaminophen and
amiodarone were introduced into … the exchange of oxygen and carbon dioxide occurs. The main …

[PDF][PDF] Drug biotransformation

MA Correia - Basic & clinical pharmacology, 2018 - academia.edu
… of intestinal metabolism of certain drugs (eg, felodipine, cyclosporine A) can also result in
significant elevation of their plasma levels and clinically relevant drug-drug interactions (DDIs, …

Role of Pharmacoproteomics

KK Jain, KK Jain - Textbook of Personalized Medicine, 2021 - Springer
… Proteomics is an important component of several interactingLovastatin treatment is
associated with signs of toxicity as … , amiodarone, tetracycline and carbon tetrachloride) that are …

[HTML][HTML] HEPATOPROTECTIVE EFFECT OF ALHAGI MAURORUM BOISS (LEGUMINOSAE) ALCOHOLIC EXTRACT AGAINST HEPATOTOXICITY IN RATS

MM El Mallah - مجلة بحوث التربية النوعية, 2016‎ - journals.ekb.eg
… Therefore, the present study was aimed to evaluate the … rich plant against carbon tetrachloride
induced hepatotoxicity … a protection against CCl4 induced hepatocyte toxicity. This was …

[HTML][HTML] The hepatic lipidome: From basic science to clinical translation

M Ten Hove, L Pater, G Storm, S Weiskirchen… - Advanced drug delivery …, 2020 - Elsevier
… -CoA is oxidized into water and carbon dioxide (CO 2 ), and … still unknown, recent research
reported the interaction between two … Furthermore, lipid accumulation in hepatocytes acts as …

Drug‐Metabolizing Enzymes and Drug Toxicity

AP Li - Transporters and Drug‐Metabolizing Enzymes in Drug …, 2021 - Wiley Online Library
… Inhibition of ALDH by carbon tetrachloride is reported to be a … Interaction of amiodarone
with racemic warfarin and its … isolated rat hepatocytes. Drug Res (Stuttg) 2016;66(11):592–96. …